与Pin2/TRF1相互作用的蛋白PinX1是一种强大的端粒酶抑制剂

X Z Zhou1, K P Lu

  • 1Cancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, HIM 1047, Boston, MA 02215, USA.

Cell
|November 10, 2001
PubMed
概括

PinX1是一种新型蛋白质,可以抑制端粒酶活性,这是细胞衰老和癌症发展的关键因素. 它的耗尽增强了瘤的生长,这表明PinX1作为瘤抑制剂.

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