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相关概念视频

Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
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CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Aortic Regurgitation I: Introduction01:15

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Myocardial Infarction and Functional Outcome Assessment in Pigs
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Published on: April 25, 2014

在急性冠状动脉封闭时,基于附带产生的心肌动脉血流的程度和大小,对最终心脏病发作大小的非侵入性预测.

M P Coggins1, J Sklenar, D E Le

  • 1Cardiovascular Imaging Center, Cardiovascular Division, University of Virginia School of Medicine, Charlottesville, VA, USA.

Circulation
|November 14, 2001
PubMed
概括

心肌对照回声学 (MCE) 可以通过在冠状动脉封闭后立即评估风险区域 (RA) 中的附带衍生心肌血流 (MBF) 来预测最终的心脏病发作大小 (IS),有助于急性心肌梗塞管理.

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科学领域:

  • 心血管成像 - 心血管成像
  • 肌肉性心脏 perfusion 的评估.
  • 心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

  • 在风险区域 (RA) 中评估附带衍生心肌动脉血流 (MBF) 可以预测冠状动脉封闭后的最终心脏病发作 (IS) 大小.
  • 担保流的变化需要准确的方法来预测IS.

研究的目的:

  • 评估心肌对照回声学 (MCE) 是否可以通过测量 RA 中的附带衍生的 MBF 来预测最终的心脏病发作大小 (IS).
  • 为了确定MCE的最佳脉冲间隔 (PI),准确评估 perfusion 缺陷.

主要方法:

  • 使用微气泡进行心肌对比回声学 (MCE) 在冠状动脉封闭 (有或没有转流) 的狗中进行.
  • 脉冲间隔 (PI) 变化以测量输液缺陷大小 (PDS).
  • 放射标记的微球和死后染色被用于分别测量MBF和IS.

主要成果:

  • 在MCE上, perfusion defect size (PDS) 与PI有所不同,与PI较短时的RA相关,与PI较长时的IS相关 (>10.6秒).
  • 由MCE衍生的MBF和微血管流速确定了缩的区域.
  • 由于MBF变异性,没有发现RA和最终IS之间的相关性.

结论:

  • 在RA冠状动脉封闭后,MCE可以立即通过量化RA冠状动脉封闭后的附带衍生MBF来确定最终心脏病发作大小 (IS).
  • 这种技术可以帮助个性化风险分层和急性心肌梗塞的管理.
  • MCE为评估心肌活力和预测心脏病发作的进展提供了有价值的工具.