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Updated: Jul 22, 2026

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通过DNA微阵列进行基因表达特征分析:有希望和陷

H C King1, A A Sinha

  • 1Department of Dermatology, Weill Medical College of Cornell University, 510 E 70th St, LC-702, New York, NY 10021, USA.

JAMA
|November 17, 2001
PubMed
概括

DNA微阵列为复杂疾病提供全基因组基因表达分析. 然而,为了获得可靠的结果,必须解决数据分析,统计有效性和功能相关性的挑战.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...