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通过NF-kappaB诱导gadd45beta会降低对亲细胞亡的JNK信号的调节

E De Smaele1, F Zazzeroni, S Papa

  • 1The Gwen Knapp Center for Lupus and Immunology research, The University of Chicago, Illinois 60637, USA.

Nature
|November 20, 2001
PubMed
概括

核因子-kappaB (NF-kappaB) 转录因子通过降低c-Jun氨基终端激酶 (JNK) 途径来促进细胞存活. 这种NF-kappaB介导的JNK信号的抑制对于控制细胞死亡至关重要.

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