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基因特异性蛋白甲基转移酶抑制剂的设计

Q Lin1, F Jiang, P G Schultz

  • 1Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|November 22, 2001
PubMed
概括

研究人员使用"撞孔"策略开发了蛋白质氨酸甲基转移酶 (PRMTs) 的新型抑制剂和基质. 这种方法可以选择性地针对特定的PRMTs,帮助研究它们在体内的功能.

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