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Updated: Jun 11, 2026

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects
07:53

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Published on: December 11, 2010

通过分子动力学模拟和蛋白质数据库搜索,研究在模型酸乙-Phe-Gly-Gly-N-甲基胺中的芳香骨胺相互作用

G Tóth1, R F Murphy, S Lovas

  • 1Department of Biomedical Sciences, School of Medicine, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA.

Journal of the American Chemical Society
|November 22, 2001
PubMed
概括

芳香环-脊柱胺基相互作用 (Ar-HN) 稳定特定的形状. 分子动力学模拟显示,这些相互作用降低了溶剂可访问性和结,影响了蛋白质结构.

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Bone Remodeling

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Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...