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Updated: Jan 8, 2026

Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface
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Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface

Published on: October 20, 2023

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CD8alphabeta核受体茎的发育调节的糖化调节了连接体结合的过程

A M Moody1, D Chui, P A Reche

  • 1Laboratory of Immunobiology, Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

Cell
|November 24, 2001
PubMed
概括

细胞分化改变了CD8β上的O-甘氨酸,影响T细胞受体结合. ST3Gal-I酶修改了这些甘氨酸,在T细胞成熟过程中降低了CD8alphabeta-MHCI狂热度.

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