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相关概念视频

Overview of the Vascular System01:20

Overview of the Vascular System

The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
Overview of Blood Vessels01:14

Overview of Blood Vessels

The human cardiovascular system comprises five primary types of blood vessels: arteries, arterioles, veins, venules, and capillaries, each serving unique functions.
Arteries and Arterioles: Arteries are muscular and elastic vessels that primarily carry oxygenated blood from the heart to body tissues, except for the pulmonary artery, which carries deoxygenated blood. They have thick walls to withstand high pressure and contain a layer of muscle tissue, allowing them to expand or contract as...
Structure of Blood Vessels01:15

Structure of Blood Vessels

Blood is circulated throughout the human body through a network of blood vessels called the circulatory system. This system includes arteries that transport blood from the heart to various body parts. These arterial pathways divide into smaller vessels until they reach the arterioles, which further split into capillaries. It is within these minuscule capillaries that the exchange of nutrients and waste products takes place. After this exchange, the blood is collected by venules, which fuse to...
Anatomy of the Heart01:20

Anatomy of the Heart

The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
Anatomy of Blood Vessels01:20

Anatomy of Blood Vessels

The vascular system, an integral part of the circulatory system, comprises various blood vessels that play crucial roles in maintaining the body's homeostasis. These blood vessels form a complex and efficient circulatory network. The three primary categories of blood vessels are the arteries, veins, and capillaries.
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta, have...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

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相关实验视频

Updated: Jul 6, 2026

Visualizing the Beating Heart in Drosophila
10:15

Visualizing the Beating Heart in Drosophila

Published on: September 28, 2009

一个基因组系统生物学地图用于心血管功能.

M Stoll1, A W Cowley, P J Tonellato

  • 1Department of Physiology, Bioinformatics Research Center, and, Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226-0509, USA.

Science (New York, N.Y.)
|November 27, 2001
PubMed
概括

研究人员在老鼠中绘制了81种心血管和脏特征,确定了特定染色体上的特征聚合物. 这种系统生物学方法有助于基因发现和转化到人类基因组学.

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Last Updated: Jul 6, 2026

Visualizing the Beating Heart in Drosophila
10:15

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Published on: September 28, 2009

Large-scale Zebrafish Embryonic Heart Dissection for Transcriptional Analysis
10:00

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Published on: January 12, 2015

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科学领域:

  • 基因组学就是基因组学.
  • 系统生物学 系统生物学
  • 身体生理学 身体生理学

背景情况:

  • 人类基因组序列的可用性需要在系统生物学框架内定义基因功能的先进方法.
  • 了解复杂的特征遗传学需要将表型数据与基因组信息整合起来.

研究的目的:

  • 在大鼠模型中绘制心血管和的表型,以确定与这些特征相关的遗传位置.
  • 通过分析基因发现和比较基因组学的生理相关性,利用系统生物学方法.

主要方法:

  • 研究了来自F2交叉的113只雄性大鼠的239种心血管和的表型.
  • 进行了81个已识别的特征的全基因组映射.
  • 分析了特征之间的相关性模式,以建立"生理学概况".

主要成果:

  • 成功地将81个心血管和脏特征映射到老鼠基因组中.
  • 鉴定出1号,2号,7号和18号染色体上的显著特征聚合物.
  • 建立了证明特征相互关系的"生理特征".

结论:

  • 已识别的特征聚合物和生理资料为心血管和系统的基因狩猎提供了基础.
  • 这项研究促进了基于机制的生理学研究.
  • 这些发现支持通过比较基因组学将大鼠基因组数据转化为人类基因组.