由水分子维持的管状键网络由水分子维持
H Carrasco1, C Foces-Foces, C Pérez
1Departamento de Bioorgánica, Instituto de Investigaciones Químicas, CSIC, Américo Vespucio, s/n, Isla de la Cartuja, 41092 Seville, Spain.
Journal of the American Chemical Society
|November 29, 2001
概括
通过弱分子间力控制晶体包装拓是功能固体的关键. 氧酸的大量替代物形成带和板,而水的柔性替代物形成3D管状网络.
科学领域:
- 超分子化学 超分子化学
- 晶体工程公司 晶体工程公司
- 有机固态化学 有机固态化学
背景情况:
- 功能性固体的设计依赖于通过弱分子间力控制晶体包装拓.
- 预测分子成分和立体化学对循环聚合物的构成的影响对于可预测的晶体结构至关重要.
研究的目的:
- 研究固体相互作用和替代剂灵活性对氧酸 (+/-) - - - - - - - - - - - - - - - - 的固态结构的影响.
- 探索基于分子结构和水合的不同超分子组件 (磁带,板,管状网络) 的形成.
主要方法:
- 合成具有一般结构 (+/-) -1 和不同替代物的氧酸.
- 用X射线晶体学来确定固态结构.
- 分析分子间相互作用,特别是键和固体效应.
主要成果:
- 化合物与重的,刚性替代物 (除了1b,1e) 通过碳酸与酒精的键形成1D带和2D片.
- 复合物 (+/-) - 1n,具有灵活的替代物,加入水,形成具有六角通道的3D管状H结合网络.
- 较小的替代剂无法形成循环聚合物,无水 (+/-) - 1n形成了板块,突出显示了水在管状结构中的作用.
结论:
- 固态相互作用和替代剂的灵活性显著决定了氧酸晶体中的超分子组合.
- 水分子在使复杂的3D管状网络形成方面发挥着关键作用.
- 这项研究表明,分子设计对所得到的固态结构具有结构指导作用.
更多相关视频
相关概念视频
Hydrogen Bonds
Hydrogen BondsHydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.Hydrogen Bonds Control the World!Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are...
Cohesion
Cohesion is the attraction between molecules of the same type, such as water molecules. Water molecules have an overall neutral charge but are polar molecule. An oxygen atom in one water molecule has a partial negative charge that can bind to a hydrogen atom with a partial positive charge in a second water molecule, forming a hydrogen bond. Each water molecule can form up to four hydrogen bonds with other water molecules. Hydrogen bonds are responsible for water's cohesive nature.
On a surface,...
On a surface,...
Intermolecular Forces
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen bonds, and dispersion...
Chemistry of the Cell
The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity and heat of...
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity and heat of...
Aquaporins
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
Tight Junctions
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...


