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相关概念视频

Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...

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A Craniotomy Surgery Procedure for Chronic Brain Imaging
09:25

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Published on: February 15, 2008

在手术期间脑瘤的异常微循环.

K R Mathura, G J Bouma, C Ince

    Lancet (London, England)
    |December 1, 2001
    PubMed
    概括

    直角偏振光谱成像可视化脑瘤的微循环. 不同类型的瘤表现出不同的血管模式和血液流动,有助于神经外科手术期间的诊断.

    科学领域:

    • 神经外科 神经外科
    • 医疗成像医学成像
    • 在瘤学瘤学.

    背景情况:

    • 微循环对于器官功能至关重要.
    • 评估脑瘤微循环有助于诊断和治疗.
    • 正交极化光谱 (OPS) 成像提供了一种可视化微血管的新方法.

    研究的目的:

    • 用OPS成像来比较脑膜瘤,质母细胞瘤和转移的功能微循环特性与正常的大脑皮层.
    • 评估OPS成像在神经外科手术中的诊断潜力.

    主要方法:

    • 使用直角偏振光谱 (OPS) 成像,这是一种采用偏振光的技术.
    • 可视化和分析了三种脑瘤类型 (脑膜瘤,脑质瘤,转移) 和正常脑皮层表面的微循环.
    • 评估血管特征,红细胞的运动和背景外观.

    主要成果:

    • 脑膜瘤表现出扩张的,混乱的血管,红细胞流量最小,背景暗.
    • 质母细胞瘤显示很少有流量较低的血管,背景类似于正常皮质.
    • 转移呈现出非常黑暗的背景,几乎没有流动,和混乱的血管系统.

    结论:

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  • OPS成像显示了不同类型脑瘤的显著微循环模式.
  • 这种技术为微循环形态和动力学提供了宝贵的见解.
  • OPS成像对神经外科手术中的手术内诊断使用具有前景.