宫内T细胞激活和增加了前发炎性细胞因子度在早产婴儿与大脑病变
Lancet (London, England)
|December 1, 2001
概括
宫内感染和炎症增加了非常早产婴儿大脑损伤的风险. 在子宫内免疫反应,通过提升的细胞因子和T细胞表明,预测新生儿的大脑病变.
科学领域:
- 新生儿神经学 新生儿神经学
- 免疫学 免疫学 免疫学
- 产周医学 产周医学
背景情况:
- 脑损伤是非常早产婴儿的一个重大问题,通常与早产前的子宫内感染有关.
- 这项研究调查了胎儿暴露于子宫内抗原/炎症和脑损伤的发展之间的联系.
更多相关视频
07:13Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
Published on: March 25, 2016
09:12Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding
Published on: November 14, 2018
相关概念视频
T Cell Types and Functions
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Development of Immunocompetence
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
