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Updated: Jul 12, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
10:34

A High-content Assay for Monitoring AMPA Receptor Trafficking

Published on: January 28, 2019

阿默沙姆生物科学与科学奖. AMPA受体的动态和突触可塑性

S H Shi1

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. shshi@itsa.ucsf.edu

Science (New York, N.Y.)
|December 1, 2001
PubMed
概括

No abstract available in PubMed .

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.