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Updated: Jul 10, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

通过CD8alphaalpha与非经典MHC I类分子TL之间的相互作用调节的T细胞反应

A J Leishman1, O V Naidenko, A Attinger

  • 1Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA.

Science (New York, N.Y.)
|December 1, 2001
PubMed
概括

胸腺白血病抗原 (TL),一个非经典的MHC I类分子,与CD8alpha相结合,而不是CD8alphabeta. 这种偏好的结合影响T细胞受体反应,揭示了新的淋巴细胞调节通路.

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