肺动脉静脉压的临床相关值和参考间隔在心声图正常的受试者中
B M McQuillan1, M H Picard, M Leavitt
1Cardiac Ultrasound, Massachusetts General Hospital, 55 Fruit St, Boston, Massachusetts, USA.
Circulation
|December 6, 2001
概括
肺动脉静脉压 (PASP) 在正常成年人中受到年龄,BMI和性别的影响. 这些因素对于确定PASP的准确正常范围至关重要,特别是在老年或肥胖个体中.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 肺高血压是什么意思 肺高血压
背景情况:
- 关于健康个体肺动脉静脉压 (PASP) 影响因素的数据有限.
- 使用大型临床心声图数据库来识别正常受试者.
研究的目的:
- 在正常人群中确定肺动脉缩压 (PASP) 的相关值.
- 使用多普勒跨胸心回声学 (TTE) 建立PASP的参考范围.
主要方法:
- 从102,818名患者的数据库中分析了15596名正常多普勒TTE研究的患者.
- 使用修改的伯努利方程计算PASP,假设右心房压力为10mmHg.
- 在PASP分析中鉴定了3790名正常TTE的受试者.
主要成果:
- 在正常人中,PASP的平均值为28.3+/-4.9 mm Hg (范围为15-57 mm Hg).
- PASP独立地与年龄,BMI,男性性别,左心室后壁厚度和喷射率 (P<0.001) 相关.
- 在低风险人群中,PASP的95%上限为37.2mm Hg;28%的PASP>30mm Hg.
结论:
- 在心声谱正常的受试者中,PASP与年龄,BMI,性别,壁厚度和喷射率有关.
- 在老年或肥胖个体中,PASP的预期上限可能会扩展到40 mm Hg.
- 建议对年龄和BMI进行校正,以确定正常的PASP范围.
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