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干细胞的自我更新由JAK-STAT激活来指定的,以响应支持细胞的提示

A A Kiger1, D L Jones, C Schulz

  • 1Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

Science (New York, N.Y.)
|December 26, 2001
PubMed
概括

德洛索菲拉丸的干细胞依赖于角枢纽细胞进行自我更新. 这些枢纽细胞通过未配对 (Upd) 连接体发出信号,激活Janus激酶信号转换器和转录激活器 (JAK-STAT) 途径,以维持生殖系干细胞群体.

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