相关实验视频

Updated: Jul 18, 2026

Chromatin Immunoprecipitation (ChIP) using Drosophila tissue
13:47

Chromatin Immunoprecipitation (ChIP) using Drosophila tissue

Published on: March 23, 2012

在Drosophila DNA中中度重复元素的聚类和杂乱的排列

P C Wensink, S Tabata, C Pachl

    Cell
    |December 1, 1979
    PubMed
    概括

    研究人员在Drosophila中发现了聚类的,中度重复的DNA元素. 这些元素在每个星团中排列不同,可以使用先进的斑点技术检测到,并且存在于euchromatic区域.

    更多相关视频

    Simple Method for Fluorescence DNA In Situ Hybridization to Squashed Chromosomes11:36

    Simple Method for Fluorescence DNA In Situ Hybridization to Squashed Chromosomes

    Published on: January 6, 2015

    Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster04:59

    Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster

    Published on: March 28, 2025

    相关概念视频

    DNA Packaging00:58

    DNA Packaging

    Overview
    Position-effect Variegation02:32

    Position-effect Variegation

    In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
    Lampbrush Chromosomes01:51

    Lampbrush Chromosomes

    In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
    LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...
    Polytene Chromosomes02:04

    Polytene Chromosomes

    Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
    Duplication of Chromatin Structure02:05

    Duplication of Chromatin Structure

    The process of chromosome duplication during cell division requires genome-wide disruption and re-assembly of chromatin. The chromatin structure must be accurately inherited, reassembled, and maintained in the daughter cells to ensure lineage propagation.
    The basic unit of the chromatin is the nucleosome, consisting of DNA wrapped around octameric histone proteins and short stretches of linker DNA separating individual nucleosomes. The histone proteins within the nucleosome have their...
    Heterochromatin02:38

    Heterochromatin

    The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
    Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...