用磁共振成像识别纤维捕获断裂与最近的过渡性缺血性发作或中风高度相关
Chun Yuan1, Shao-xiong Zhang, Nayak L Polissar
1Department of Radiology, University of Washington, Seattle 98195, USA. cyuan@u.washington.edu
Circulation
|January 16, 2002
概括
磁共振成像 (MRI) 可以识别在动脉样硬化中破裂的纤维帽. 破裂的帽子与最近的过渡性缺血性攻击 (TIA) 或中风有很强的联系,表明高风险.
科学领域:
- 血管成像 血管成像
- 脑血管疾病是脑血管疾病.
- 动脉样硬化的成像成像
背景情况:
- 高分辨率的MRI可以在体内区分心血管斑块纤维盖的完整性 (厚,薄,破裂).
- 动脉动脉样硬化斑块破裂是中风发病的一个关键事件.
研究的目的:
- 为了确定MRI识别的纤维帽薄化或破裂是否与最近的过渡性缺血性攻击 (TIA) 或中风相关.
- 评估带斑块形态与最近的脑血管事件之间的关联.
主要方法:
- 53名接受动脉内关节切除术的患者接受了手术前的动脉MRI.
- 分析了MRI扫描,使用既定的标准来分类纤维帽状况 (完整-厚,完整-薄,破裂).
- 在有或没有近期TIA或中风病史的患者之间比较了Cap状态.
主要成果:
- 一个显著的趋势显示,症状患者 (最近的TIA/中风) 的百分比较高,头顶破裂 (70%) 与厚头顶 (9%) 相比.
- 纤维帽破裂的患者与厚帽患者相比,最近发生TIA或中风的可能性是23倍.
- 纤维捕获断裂的MRI识别表明与最近的缺血事件有很强的关联.
结论:
- 破裂纤维状盖的MRI检测与最近的TIA或中风高度相关.
- 通过MRI可视化的带斑块纤维帽特征可以预测未来的缺血事件.
- 需要进一步的前性研究来确认MRI衍生的帽子特征的预测价值.
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