Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

252
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
252
Cancer Vaccines01:30

Cancer Vaccines

917
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
917
Development of Immunocompetence01:22

Development of Immunocompetence

759
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
759
Vaccinations01:51

Vaccinations

51.1K
Overview
51.1K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Teratogenicity01:07

Teratogenicity

3.9K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Continental-wide prioritization of protected areas to address global and habitat-specific goals for avian biodiversity conservation.

Conservation biology : the journal of the Society for Conservation Biology·2026
Same author

Obstructive sleep apnea, glycemic control, and cardiovascular risk in young adults with youth-onset type 2 diabetes: results from the TODAY study.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2025
Same author

Brief report: Validity of self-report measures of medication adherence in young adults with youth-onset type 2 diabetes.

Diabetes research and clinical practice·2025
Same author

Psychosocial predictors of diabetes self-efficacy in young adults with youth-onset type 2 diabetes.

Journal of behavioral medicine·2025
Same author

Psychosocial Factors and Glycemic Control in Young Adults With Youth-Onset Type 2 Diabetes.

JAMA network open·2024
Same author

Genetic and pharmacological modulation of lamin A farnesylation determines its function and turnover.

Aging cell·2024

相关实验视频

Updated: Jan 6, 2026

Mitral Valve Prolapse III: Nursing Management
01:19

Mitral Valve Prolapse III: Nursing Management

Published on: June 19, 2025

252

细胞质氨酸作为核包膜分解的促进剂.

Davide Salina1, Khaldon Bodoor, D Mark Eckley

  • 1Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.

Cell
|January 17, 2002
PubMed
概括

迪内因运动蛋白在细胞分裂过程中拉动核外,促进核外的分解. 破坏dynein功能会改变核膜动态,支持其在这个过程中的作用.

科学领域:

  • 细胞生物学 细胞生物学
  • 分子生物学分子生物学
  • 显微镜的使用方法

背景情况:

  • 在预相过程中,较高的真核细胞中的中枢细胞通过微管相互作用迁移到核外.
  • 核包膜分解 (NEBD) 是线粒分裂的一个关键事件,始于 prometaphase.

研究的目的:

  • 为了研究dynein运动蛋白在细胞分裂期间核包膜分解中的作用.
  • 阐明dynein影响核膜动态的机制.

主要方法:

  • 在较高的真核细胞中,活细胞对神经分裂的成像.
  • 微管破坏测试. 微管破坏测试.
  • 对dynein和dynactin复合物局部化的分析.
  • 与dynein活动的功能干扰.

主要成果:

  • 在核结构明显变化之前,dynein 和 dynactin 复合体会在核外上积聚.
  • 核包膜分解开始在与中心体相关的发酵区域之外的区域.
  • 对dynein功能的干扰在预相和前相期间显著破坏了核膜动力学.

结论:

更多相关视频

Cancer Vaccines
01:30

Cancer Vaccines

917
Development of Immunocompetence
01:22

Development of Immunocompetence

759

相关实验视频

Last Updated: Jan 6, 2026

Mitral Valve Prolapse III: Nursing Management
01:19

Mitral Valve Prolapse III: Nursing Management

Published on: June 19, 2025

252
Cancer Vaccines
01:30

Cancer Vaccines

917
Development of Immunocompetence
01:22

Development of Immunocompetence

759
  • 迪内因运动蛋白对于核外分解至关重要,它通过沿着星际微管道对核外施加极向力.
  • 这种机制涉及通过dynein介导的拉力,导致核膜脱离.
  • 这些发现支持dynein主动驱动NEBD的模型.