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Updated: Jun 15, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

替代核酸切割修复途径用于氧化DNA损伤的替代核酸切割修复途径

Alexander A Ischenko1, Murat K Saparbaev

  • 1Groupe "Réparation de l'ADN", UMR 8532 CNRS, LBPA-ENS Cachan, Institut Gustave Roussy, 94805 Villejuif Cedex, France.

Nature
|January 24, 2002
PubMed
概括

另一种替代的DNA修复途径绕过了DNA糖酶系统,该系统与氧化损伤作斗争. 类似Nfo的内核酶通过在氧化基附近断DNA来启动修复,从而为随后的合成创造了合适的末端.

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