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相关概念视频

Anatomy of the Heart01:27

Anatomy of the Heart

The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Anatomy of the Heart01:20

Anatomy of the Heart

The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...

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相关实验视频

Updated: Jul 18, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
11:29

A Modified Method for Heterotopic Mouse Heart Transplantion

Published on: June 23, 2014

失败的心脏失败的心脏.

J A Towbin1, N E Bowles

  • 1Department of Pediatrics (Cardiology), Baylor College of Medicine, Houston, Texas 77030, USA. jtowbin@bcm.tmc.edu

Nature
|January 24, 2002
PubMed
概括

心肌病,导致心力衰竭的心肌疾病,越来越多地通过遗传进步来理解. 这些知识改善了诊断,并为这种常见疾病的新疗法铺平了道路.

科学领域:

  • 心脏病学 心脏病学
  • 遗传学 是一个遗传学.
  • 分子生物学分子生物学

背景情况:

  • 心肌病是一种导致心力衰竭的心肌疾病.
  • 它们是导致死亡的重要原因,特别是在美国.
  • 最近的研究集中在这些条件的分子基础上.

研究的目的:

  • 为了突出了解心肌病的最新突破.
  • 强调有关心肌病遗传基础的知识进步.
  • 讨论对诊断策略和治疗开发的影响.

主要方法:

  • 关于心肌病的最新科学文献的综述.
  • 对分子和遗传研究结果的分析.
  • 综合有关诊断和治疗进展的信息.

主要成果:

  • 在阐明心肌病的分子机制方面取得了重大进展.
  • 遗传研究为这些心脏病的病因提供了大量的见解.
  • 这些进展对于开发改进的诊断工具至关重要.

结论:

  • 了解心肌病的遗传基础正在改变临床实践.

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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

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相关实验视频

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A Modified Method for Heterotopic Mouse Heart Transplantion
11:29

A Modified Method for Heterotopic Mouse Heart Transplantion

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Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
09:40

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Published on: May 13, 2019

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

  • 基于分子和遗传发现的新诊断策略正在出现.
  • 这项研究为开发针对心肌病的向治疗奠定了基础.