术前吸烟干预对术后并发症的影响:一项随机临床试验
Ann M Møller1, Nete Villebro, Tom Pedersen
1Department of Anaesthesiology, Bispebjerg University Hospital, 2400 NV, Copenhagen, Denmark. docamm@yahoo.com
Lancet (London, England)
|January 26, 2002
概括
手术前的吸烟干预显著减少了关节和膝关节置换患者的术后并发症. 这种戒烟计划降低了整体发病率,建议采用.
科学领域:
- 整形外科手术 整形外科手术
- 公共卫生 公共卫生
- 临床干预研究 临床干预研究
背景情况:
- 吸烟者在手术后面临心肺和伤口并发症的风险增加.
- 吸烟的部和膝盖置换患者经历了更高的不良结果率.
研究的目的:
- 评估手术前吸烟干预对术后并发症频率的影响.
- 在骨科手术前评估戒烟或减少吸烟计划的有效性.
主要方法:
- 一项随机试验,涉及120名接受关节和膝盖置换手术的患者.
- 干预组在手术前6-8周接受咨询和尼古丁替代疗法.
- 包括并发症和住院住院在内的结果由蒙面观察员评估.
主要成果:
- 吸烟干预组的整体并发症率为18%,对照组为52% (p=0.0003).
- 观察到伤口并发症 (5%与31%,p=0.001) 和二次手术率 (4%与15%,p=0.07) 的显著减少.
- 干预组的中位数住院时间较短 (11天 vs 13天).
结论:
- 手术前的吸烟干预计划有效地减少了骨科手术患者的术后发病率.
- 该研究建议采用这种吸烟干预计划,以改善手术结果.
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