双极性障碍是一种双极性障碍
Bruno Müller-Oerlinghausen1, Anne Berghöfer, Michael Bauer
1Department of Psychiatry, Research Group of Clinical Psychopharmacology, Freie Universität Berlin, Berlin, Germany.bmoe@zedat.fu-berlin.de
Lancet (London, England)
|January 29, 2002
概括
双极性障碍是一种严重的情绪障碍,患病率和自杀率很高. 盐是双相情感障碍的主要长期治疗方法,具有已证明的抗自杀作用.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 情绪障碍 情绪障碍 情绪障碍
背景情况:
- 双极性障碍 (躁狂抑郁症) 是一种常见的,严重的,经常性情绪障碍,具有显著的发病率.
- 终身患病率为1.3-1.6%,死亡率是一般人口的2-3倍.
- 自杀风险很大,10-20%的患者死于自杀,近三分之一的患者尝试过自杀.
研究的目的:
- 审查双相情感障碍的特征和治疗方法.
- 强调长期预防治疗的重要性.
- 讨论不同药理干预措施的有效性.
主要方法:
- 对双相情感障碍现有文献的综述.
- 对流行率,发病率和死亡率数据的分析.
- 药理治疗选择的评估,包括,碳胺和氨酸.
主要成果:
- 双极性障碍呈现出各种不同的临床表现,从低躁狂到严重的精神病.
- 由于复发和自杀风险很高,长期预防性药物治疗是必不可少的.
- 盐是第一线治疗,显示出显著的抗自杀作用.
- 碳胺和氨酸是第二选择的选择,证据不那么坚实.
结论:
- 双极性障碍需要长期管理,以减轻复发和自杀风险.
- 仍然是双相情感障碍预防治疗的黄金标准.
- 可能需要进一步的研究来加强对二线治疗的证据.
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