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Updated: May 5, 2026

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Th1 特定的细胞表面蛋白 Tim-3 调节巨细胞激活和自身免疫性疾病的严重程度

Laurent Monney1, Catherine A Sabatos, Jason L Gaglia

  • 1Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|February 2, 2002
PubMed
概括

研究人员在Th1细胞上发现了Tim-3,一个新的表面分子. 阻断Tim-3使实验性自身免疫性脑膜炎恶化,这表明Tim-3调节了自身免疫性疾病中的免疫反应和巨细胞激活.

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