相关实验视频

Updated: Jul 11, 2026

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

在回声心脏学证明的细分性动力障碍和区域性心肌 perfusion 之间的相关性

R E Kerber, M L Marcus, J Ehrhardt

|December 1, 1975

概括

减少心肌输液与心脏壁运动异常有很强的相关性,包括动脉瘤膨胀和减速. 即使在再注射后,这些运动问题仍然存在,影响邻近的健康组织.

科学领域:

心血管生理学心血管生理学
心肌输血成像 - - 心肌输血成像
心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

评估血液流动和心肌运动之间的关系对于理解心脏功能障碍至关重要.
心肌缺血可以导致心脏壁运动的显著改变.

研究的目的:

为了研究区域性心肌输液和细分心脏功能障碍之间的相关性.
评估冠状动脉封闭和再注射对心肌输血和心肌壁运动的影响.

主要方法:

利用开放胸部的狗进行心脏壁运动的超声波和心肌输液的放射性微球.
在部分和完整的环冠状动脉封闭过程中,相关的输液和运动.
评估的效果是45分钟的闭塞,然后30分钟的再输液.

主要成果:

在同位数收缩期间,输液下降和动脉瘤膨胀之间存在强烈的负相关性 (r = -0.80).
在缩喷射期间, perfusion 和内心壁速度之间存在强烈的正相关性 (r = 0.92).
重灌后,输液正常化,但动脉瘤膨胀仍然存在;墙壁运动速度显示可变的恢复.

结论:

区域性心肌输液与心脏壁运动异常直接相关.
肌动脉麻醉和动力障碍甚至在恢复血液流动后也可能持续存在.
邻近的正常透的心肌可以由于缺血段的机械作用而表现出异常.

更多相关视频

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

Published on: October 11, 2022

相关概念视频

Pathophysiology of Cardiac Performance

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...

Imbalances in Cardiac Output

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...