晚期心力衰竭的医疗管理
Anju Nohria1, Eldrin Lewis, Lynne Warner Stevenson
1Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St, Tower 3-A, Boston, MA 02115, USA.
JAMA
|February 7, 2002
概括
目前的高级心力衰竭管理依赖于共识,而不是试验. 优化现有疗法和探索新疗法对于更好的患者结果和减少再入院至关重要.
科学领域:
- 心脏病学 心脏病学
- 内部医学 内部医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 晚期心力衰竭显著导致发病率和死亡率.
- 它的特点是,尽管有有效的治疗方法,但持续存在限制性症状.
研究的目的:
- 审查目前针对晚期心力衰竭的医疗治疗.
- 确定在高级心力衰竭管理中进行系统调查的领域.
主要方法:
- 在MEDLINE,EMBASE,最佳证据,基于证据的医学和科克莱恩图书馆 (1980-2001) 的综合文献搜索.
- 包括随机对照试验 (≥150名患者) 和其他相关临床数据.
- 通过同行评审的出版物或专业协会指南评估数据质量.
主要成果:
- 管理侧重于识别和治疗高填充压力.
- ангиотензин转化酶抑制剂和β-上腺素药物可以减缓进展,但面临着定位挑战.
- 量身定制的医疗方案和心力衰竭管理计划减少了再住院治疗;生存率随症状严重程度而有很大差异.
结论:
- 目前的高级心力衰竭管理在很大程度上是基于共识的.
- 需要对新型疗法进行系统的研究,并优化现有疗法.
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