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Updated: Jun 24, 2026

Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli
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Published on: November 30, 2018

使用一个珠子/一个库存溶液平台,以多样性为导向的二甲基含有二甲基的中环合成

David R Spring1, Shyam Krishnan, Helen E Blackwell

  • 1Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Institute of Chemistry and Cell Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|February 14, 2002
PubMed
概括

这项研究开发了一种新的方法,用于合成各种复杂的小分子,使用珠子上的有机酸盐氧化. 这种化学遗传学方法可以通过大型化合物库有效地探索生物途径.

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