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Updated: Jul 8, 2026

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
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Published on: June 20, 2014

一个结合性的支架方法,朝着酶导向的异环库

Sheng Ding1, Nathanael S Gray, Xu Wu

  • 1Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|February 21, 2002
PubMed
概括

研究人员开发了一种用于合成各种异环化合物的新方法,用于酶导向库. 这种方法可以创建各种小分子用于生物查.

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相关概念视频

Restriction Enzymes01:11

Restriction Enzymes

Restriction enzymes are bacterial enzymes used to cut DNA in a sequence-specific manner. To cleave DNA, they bind to specific palindromic sequences called restriction sites. Such palindromic DNA sequences or inverted repeats are commonly found in regions of functional significance, such as the origin of replication, gene operator sites, and regions containing transcription termination signals.
The host bacteria protect their own genomic DNA from these enzymes by methylating these sites. Some...