特定的Stat3beta消去会扭曲Stat3响应基因表达的模式,并阻碍从内毒性冲击中恢复

Joo-Yeon Yoo1, David L Huso, Daniel Nathans

  • 1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Baltimore, MD, USA.

Cell
|February 21, 2002
PubMed
概括

Stat3beta是一种蛋白质异型,对控制全身炎症至关重要. 缺乏Stat3beta的小鼠在内毒性休克后的恢复受损,突出显示其在免疫反应中的作用.

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