肺静脉隔离对于心脏动和持续性心房动
Hakan Oral1, Bradley P Knight, Hiroshi Tada
1Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. oralh@umich.edu
Circulation
|March 6, 2002
概括
分段性肺静脉隔离有效地治疗心房动 (AF) 在大多数偏激性AF患者. 这种程序显示持续性AF的成功率较低,突出了AF管理中的患者特异性结果.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 肺静脉 (PVs) 经常与心房 (AF) 的产生有关.
- 分段性肺静脉隔离是AF管理的潜在治疗策略.
研究的目的:
- 评估细分肺静脉隔离的安全性和有效性.
- 评估患有心脏动或持续性心脏动的患者的结局.
主要方法:
- 分段性肺静脉隔离在70名患有发性 (58) 或持久性 (12) AF 的患者中进行.
- 应用射频能量来隔离轴心光伏潜力;230个目标光伏中的217个 (94%) 被隔离.
- 5个月后进行随访,以评估没有复发的AF和症状改善.
主要成果:
- 70%的阳性AF患者和22%的持续性AF患者在5个月后没有复发性AF.
- 83%的阳性AF患者没有出现症状性AF或明显改善.
- 囊性AF是唯一一个独立的预测器,可以预测AF不会复发 (P<0.05).
- 一名患者经历了单侧四角;没有报告其他并发症.
结论:
- 针对至少3个PV的细分PV隔离在超过80%的阳性AF患者中取得了令人满意的临床结果.
- 肺静脉隔离的疗效在持久性AF中明显较低,而不是帕洛西斯马尔AF.
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