肺癌,心肺死亡率和长期暴露于细颗粒物空气污染的风险
C Arden Pope1, Richard T Burnett, Michael J Thun
1Department of Economics, Brigham Young University, 142 FOB, Provo, UT 84602, USA. cap3@email.byu.edu
JAMA
|March 7, 2002
概括
长期接触细颗粒物空气污染会显著增加死于肺癌和心肺疾病的风险. 这种环境风险因素凸显了空气质量对健康的影响.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 空气中的颗粒物污染与不良健康结果有关,包括心肺死亡率.
- 之前对空气颗粒污染长期影响的研究得出了不确定的结果.
研究的目的:
- 调查长期暴露于细颗粒物空气污染和死亡率之间的关联.
- 评估所有原因,肺癌和心肺死亡率的风险.
主要方法:
- 利用美国癌症协会的癌症预防II前性死亡率研究的数据 (大约. 1982年注册的成年人数为120万).
- 关联个人风险因素数据 (基于问卷) 约50万成年人与美国大都会地区空气污染数据.
- 综合数据与生命状态和死亡原因信息,截至1998年12月31日.
主要成果:
- 细颗粒物和氧化硫污染与所有原因,肺癌和心肺死亡率的增加有关.
- 细颗粒气体空气污染量增加10μg/m3对应于所有原因,心肺和肺癌死亡率分别增加4%,6%和8%的风险.
- 粗粒子分数和总悬浮粒子没有显示出一致的死亡率关联.
结论:
- 长期暴露于与燃烧相关的细颗粒物空气污染是一个重要的环境风险因素.
- 这种暴露与心肺疾病和肺癌的死亡率增加有关.
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