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相关概念视频

What are Proteins?01:55

What are Proteins?

Overview
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibody Structure and Classes01:25

Antibody Structure and Classes

Antibodies, also known as immunoglobulins, are produced by B cells in response to foreign substances, such as bacteria and viruses. These proteins are critical for recognizing and neutralizing these substances, protecting the body from potential harm.
The basic structure of an antibody consists of four protein chains: two identical heavy chains and two identical light chains. These chains are held together by disulfide bonds and other non-covalent interactions, forming a Y-shaped structure.

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The -216- to -100-bp Sequence in the 5'-Flanking Region of the Oxytocin Gene Contains a Cell-Type Specific Regulatory Element for its Selective Expression in Oxytocin Magnocellular Neurones.

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Cell-type specific expression of oxytocin and vasopressin genes: an experimental odyssey.

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Cell-specific expression of the rat oxytocin gene in transgenic mice.

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Corticotrophin-Releasing Hormone Stimulates Neurohypophyslal Hormone Release through an Interaction with the Intermediate Lobe of the Pituitary.

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Differential kinetics of oxytocin and vasopressin heteronuclear RNA expression in the rat supraoptic nucleus in response to chronic salt loading in vivo.

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相关实验视频

Updated: Jul 5, 2026

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
11:17

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

类动物胃蛋白:度和分子形式

E Straus, R S Yalow, H Gainer

    Science (New York, N.Y.)
    |November 14, 1975
    PubMed
    概括

    在哺乳动物中发现的激素胃素,也存在于海和陆地牛中. 它的存在和度表明,软体动物和哺乳动物的胃蛋白之间存在结构上的相似之处.

    科学领域:

    • 比较生理学比较生理学
    • 内分泌学 在内分泌学.
    • 海洋生物学 海洋生物学

    背景情况:

    • 胃蛋白是一种关键的激素,调节哺乳动物的胃肠功能.
    • 以前的研究主要集中在脊椎动物系统中的胃素上.

    研究的目的:

    • 为了研究软体动物物种中胃素的存在和特征.
    • 探索软体动物和哺乳动物胃肠之间潜在的结构同质性.

    主要方法:

    • 血液和胃肠组织中的胃素的免疫组合化学分析.
    • 使用猪胃素标准量化胃素度.

    主要成果:

    • 在海 (Aplysia californica) 和陆地牛 (Otala lactea) 中检测到异质形式的免疫反应性胃素.
    • 这些软体动物的血液中胃素度与猪,人类和狗等哺乳动物中观察到的度相当.

    结论:

    • 软体动物的胃蛋白与哺乳动物的胃蛋白具有结构上的相似之处,这表明进化保存.
    • 这项研究扩大了我们对脊椎动物之外的胃素存在的理解,表明了更广泛的生物学作用.

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