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Updated: May 12, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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Published on: March 12, 2013

导致布鲁加达和长QT综合征表型的Na(+) 通道突变:对机制的模拟研究

Colleen E Clancy1, Yoram Rudy

  • 1Cardiac Bioelectricity Research and Training Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207, USA.

Circulation
|March 13, 2002
PubMed
概括

一个心脏Na(+) 通道突变 (1795insD) 矛盾地导致长QT和布鲁加达综合征. 计算模型显示,这种突变不同影响心脏细胞,解释了各种临床结果.

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