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Updated: Jun 6, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

瘤坏死因子-α调节胰岛素样生长因子-1和胰岛素样生长因子结合蛋白-3在血管光滑肌肉中的表达

A Anwar1, A A Zahid, K J Scheidegger

  • 1Division of Cardiology, University Hospital of Geneva, Switzerland.

Circulation
|March 13, 2002
PubMed
概括

瘤亡因子-α (TNF-α) 降低胰岛素样生长因子-1 (IGF-1) 并增加血管光滑肌细胞中的IGF结合蛋白-3 (IGFBP-3). 这种TNF-α对IGF-1的下调可能会促进冠状动脉综合征中的斑块不稳定性.

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