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基于Hoogsteen的DNA的平行链双重复制. 8-氨基纯素衍生物的作用

Elena Cubero1, Anna Aviñó, Beatriz G de la Torre

  • 1Departament de Bioquímica i Biologia Molecular, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1, Barcelona 08028, Spain.

Journal of the American Chemical Society
|March 21, 2002
PubMed
概括

这项研究揭示了平行链DNA重复体利用Hoogsteen动机,而不是逆向的沃森-克里克动机. 8-氨基基替代物显著稳定了这些结构,这表明在基因调节的DNA三重组中有应用.

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