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Detection of Protein Ubiquitination
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Published on: August 19, 2009

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一个单一的基因因子,负责内细胞蛋白中的泛素识别和单一泛素化

Simona Polo1, Sara Sigismund, Mario Faretta

  • 1Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy.

Nature
|March 29, 2002
PubMed
概括

单基化是一种关键的蛋白质修饰,在像Eps15.15这样的内细胞蛋白中由基相互作用基因 (UIM) 介导. 这种UIM有助于ubiquitin识别和monoubiquitination,形成一个新的细胞内网络.

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