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Updated: Jul 13, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
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A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene

Published on: April 1, 2019

在华法林治疗期间,CYP2C9遗传变异与抗凝相关结果之间的关联

Mitchell K Higashi1, David L Veenstra, L Midori Kondo

  • 1University of Washington, Department of Pharmacy, Box 357630, Health Sciences Bldg, Room H-375A, Seattle, WA 98195, USA.

JAMA
|April 3, 2002
PubMed
概括

在服用华法林的患者中,CYP2C9 (cytochrome P450 2C9) 的遗传变异增加了过度抗凝和出血事件的风险. 查这些CYP2C9变异可能有助于个性化华法林剂量,并减少药物不良反应.

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