与可卡因可卡因有关的急性大动脉解剖
Priscilla Y Hsue1, Cynthia L Salinas, Ann F Bolger
1Division of Cardiology, San Francisco General Hospital, CA 94110, USA.
Circulation
|April 3, 2002
概括
吸食可卡因,特别是可卡因,是城市内人口急性大动脉解剖的常见原因. 这种情况经常影响年轻人,需要立即接受医疗治疗.
科学领域:
- 心脏病学 心脏病学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 急性大动脉解剖是一种危及生命的疾病.
- 它与可卡因使用的关联并未得到广泛认可.
- 与可卡因有关的大动脉剖析的特征仍然没有定义.
研究的目的:
- 确定与可卡因有关的急性大动脉剖析的特征.
- 评估可卡因使用者中大动脉剖析的患病率.
主要方法:
- 医院病历 (1981-2001年) 的回顾性审查,ICD-9诊断为大动脉剖析.
- 对38例急性大动脉解剖病例的分析.
- 与可卡因有关的和与可卡因无关的剖析组之间的比较.
主要成果:
- 14% (37%) 的急性大动脉剖析与可卡因使用有关 (主要是可卡因).
- 与可卡因相关的剖析发生在年轻的患者身上,通常是黑色的未经治疗的高血压患者.
- 可卡因使用和症状出现之间的间隔平均为12小时.
结论:
- 与使用裂可卡因相关的急性大动脉剖析在城市内人口中很普遍.
- 这很可能是由于可卡因引起的高血压和catecholamine释放.
- 考虑在患有严重胸痛和疑似大动脉剖析的患者中使用可卡因.
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