在静脉注射非离子放射学对比剂后致命的非心脏性肺 oedema
1Accident and Emergency Department, Horton Hospital, OX16 9AL, Banbury, UK.
Lancet (London, England)
|April 9, 2002
概括
致命的非心脏性肺发生在接受常见放射性对比剂IOPAMIDOL的患者身上. 这种罕见的,危及生命的反应凸显了进一步了解对比介质不良事件的需要.
科学领域:
- 放射学 放射学是一门学科.
- 药理学 药理学是指药理学的学科.
- 临界护理医学 临界护理医学
背景情况:
- 放射性对比介质是必要的诊断工具.
- 对比媒体的不良反应虽然很少见,但可能很严重.
- 胺醇是一种广泛使用的低度,非离子放射性对比介质.
研究的目的:
- 报告一种罕见的致命的非心脏性肺瘤病例,该病例是在静脉注射iopamidol后发生的.
- 为了强调对比引起的肺的独特的临床表现和潜在的严重程度.
主要方法:
- 病例报告详细介绍了一名患者对静脉注射阳胺的经验,用于静脉注射泌尿图.
- 临床观察症状,诊断成像 (胸部放射) 和治疗干预措施.
- 审查患者的病史,包括膀瘤和出血症.
主要成果:
- 一名患者在接受100毫升IOPAMIDOL后不久就出现了急性,严重的肺.
- 患者经历了呼吸困难和肺的放射证据.
- 尽管接受了治疗,但患者最终死于这种疾病.
结论:
- 对比诱导的非心脏性肺,虽然很少见,但可能危及生命.
- 这种特定类型的对比诱导肺的发病原因仍然不太清楚.
- 对比剂诱导的非心脏性肺的治疗策略与心脏性肺的治疗策略不同.
相关概念视频
Parenteral Anesthetics: Overview
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Pneumothorax-I
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Cardiac Catheterization IV: Nursing Management
Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
Cardiopulmonary Resuscitation IV: Pharmacological Management
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
Pulmonary Edema II: Pathophysiology
Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...


