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Updated: May 8, 2026

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates
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Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

Published on: March 31, 2012

P-Rex1,一个PtdIns(3,4,5) P3-和Rac Rac的Gbetagamma调节的关氨核酸交换因子

Heidi C E Welch1, W John Coadwell, Christian D Ellson

  • 1Inositide Laboratory, Cambridge CB2 4AT, United Kingdom.

Cell
|April 17, 2002
PubMed
概括

研究人员确定了P-Rex1,一种新的Rac激活剂,对中性粒细胞信号传递至关重要. 这种关氨酸核酸交换因子 (GEF) 被特定的脂质和G蛋白子单元激活,影响细胞反应.

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