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Updated: Jun 11, 2026

Effect of Anti-c-fms Antibody on Osteoclast Formation and Proliferation of Osteoclast Precursor In Vitro
07:51

Effect of Anti-c-fms Antibody on Osteoclast Formation and Proliferation of Osteoclast Precursor In Vitro

Published on: March 18, 2019

兰克尔通过c-Fos依赖的干扰素-β诱导维持骨质平衡

Hiroshi Takayanagi1, Sunhwa Kim, Koichi Matsuo

  • 1Department of Immunology, Faculty of Medicine and Graduate School of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

Nature
|April 19, 2002
PubMed
概括

NF-kappaB连接体 (RANKL) 的受体激活剂在骨质细胞前体中诱导干扰素-β (IFN-β). 然后,这种IFN-β抑制了骨质细胞分化,揭示了骨质稳定的一种新型调节途径.

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