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Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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7-N-(基基) 米托基因:循环化对药物功能的影响

Younghwa Na1, Shuang Wang, Harold Kohn

  • 1Department of Chemistry, University of Houston, Houston, Texas 77204-5641, USA.

Journal of the American Chemical Society
|April 25, 2002
PubMed
概括

新的方法成功地合成和表征了米托米C (MMC) 和皮罗米 (PFC) 硫醇. 醇的结构和稳定性取决于基连接剂,较长的连接剂促进自由醇的形成,而不是循环化或环激活.

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