年轻男性的冠状动脉影像
C C Welch1, W L Proudfit, F M Sones
1Department of Clinical Cardiology, Department of Cardiovascular Disease and Cardiac Laboratory, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Circulation
|October 1, 1970
概括
冠状动脉疾病在40岁以下的男性中普遍存在,近一半的人表现出显著的狭窄. 胆固醇水平与冠状动脉病变的存在和严重程度密切相关.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 冠状动脉疾病 (CAD) 通常与老年人群有关.
- 患有胸痛的年轻人经常接受CAD的诊断评估.
研究的目的:
- 调查40岁以下男性冠状动脉狭窄的患病率和特征.
- 为了将血管学发现与临床症状,心电图 (ECG) 结果和胆固醇水平相关联.
主要方法:
- 在40岁以下的723名患有胸痛的男性中进行了冠状动脉动图.
- 分析包括病变分布,严重程度和与心电图,左心室图和血清胆固醇的相关性.
主要成果:
- 49%的男性有显著的冠状动脉狭窄 (≥50%).
- 前下垂动脉最常受到影响;右冠状动脉显示了最完全的遮.
- 较高的胆固醇水平 (>275毫克/100毫升) 与较低的胆固醇水平 (<200毫克/100毫升,20%) 相比,与明显更高的CAD流行率 (81%) 有关.
结论:
- 显著的冠状动脉狭窄在被评估为胸痛的年轻男性中很常见.
- 胆固醇水平是这一人口群体中CAD风险的关键指标.
- 血管图检测结果与临床诊断的相关性很好,特别是在典型的表现中.
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