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Updated: May 3, 2026

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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常见的雌激素受体多态性增加了激素替代疗法对E-选择素的影响,但不是C-反应蛋白的影响

David M Herrington1, Timothy D Howard, K Bridget Brosnihan

  • 1Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1045, USA. kklein@wfubmc.edu

Circulation
|May 9, 2002
PubMed
概括

雌激素受体-alpha (ER-alpha) IVS1-401 C/C基因型增强激素替代疗法 (HRT) 减少E-选择蛋白,但不是C反应蛋白 (CRP). 这种多态化为B-myb创建了一个结合点,影响雌激素的作用.

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