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维生素D受体作为肠道胆酸传感器

Makoto Makishima1, Timothy T Lu, Wen Xie

  • 1Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9050, USA.

Science (New York, N.Y.)
|May 23, 2002
PubMed
概括

维生素D受体 (VDR) 与胆酸石化酸 (LCA) 结合,这种化合物与肝脏毒性和癌症有关. 这种相互作用可能解释了维生素D如何保护结肠癌.

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