如何在医学研究中使用统计专业知识
Douglas G Altman1, Steven N Goodman, Sara Schroter
1Centre for Statistics in Medicine, Cancer Research UK/NHS, Institute of Health Sciences, Old Rd, Headington, Oxford OX3 7LF, England. doug.altman@cancer.org.uk
JAMA
|June 1, 2002
概括
统计专业知识在医学研究中至关重要,但往往是迟迟获得的,而且没有得到承认. 研究表明,没有统计输入的研究面临更高的拒绝率,影响出版成功.
科学领域:
- 医学研究方法论医学研究方法论.
- 生物统计学 生物统计学
- 科学出版物科学出版物.
背景情况:
- 调查统计专业知识在医学研究中的作用和频率.
- 检查统计输入和编辑决策之间的关系.
研究的目的:
- 确定统计学家参与医学研究的程度.
- 评估统计输入对手稿接受和拒绝的影响.
主要方法:
- 在BMJ和Annals of Internal Medicine提交的作者中进行的调查 (2001年5月至8月).
- 关于统计援助的问卷,其性质和缺失原因.
- 基于统计输入的响应率和编辑结果的分析.
主要成果:
- 75%的响应率;73%的论文报告了方法论投入,主要来自生物统计学家/流行病学家.
- 统计输入通常与作者身份有关,但27%的方法学家都没有得到.
- 没有统计辅助的研究更有可能在没有审查的情况下被拒绝 (71%对57%),并且可能不太可能被接受 (7%对11%).
结论:
- 建议统计输入,但在医学研究中不一致地获得.
- 统计专家经常在过程中 (数据分析) 参与到后期,并且往往没有得到承认.
- 缺乏统计输入可能会对手稿审查和出版结果产生负面影响.
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