相关实验视频
Updated: May 5, 2026

08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
13.7K
拒绝或不适合选择性修复的患者的大腹大动脉动脉瘤的破裂率
Frank A Lederle1, Gary R Johnson, Samuel E Wilson
1Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minn 55417, USA. frank.lederle@med.va.gov
JAMA
|June 8, 2002
概括
患有大腹主动脉动脉瘤 (AAA) 的高风险患者面临相当大的破裂风险. 这种风险在较大的动脉瘤直径,特别是7.0厘米或更大的动脉瘤时显著增加.
科学领域:
- 血管外科 血管外科
- 大动脉动脉瘤研究研究
- 患者风险分层患者风险分层
背景情况:
- 在高风险患者中,腹腔大动脉瘤 (AAA) 修复通常会被推迟,直到破裂迫在眉.
- 关于该群体中大型AAA的破裂风险的数据有限.
- 目前的指导方针缺乏对大型AAA的精确破裂风险数据.
研究的目的:
- 为了确定患有大腹主动脉动脉瘤 (AAA) 的患者中破裂的发生率.
- 为了提供AAA破裂风险的数据,按直径分层分层.
- 为高手术风险AAA患者的临床决策提供信息.
主要方法:
- 在47个退伍军人事务医疗中心进行的前性队列研究.
- 招募了198名高手术风险的退伍军人,AAA至少为5.5厘米,不包括那些计划进行可选修复的退伍军人.
- 随访患者平均1.52年,根据初始和达到的直径评估AAA破裂发生率.
主要成果:
- 一年可能发生的AAA断裂发生率为5.5-5.9厘米的9.4%,6.0-6.9厘米的10.2%,AAA≥7.0厘米的32.5%.
- 达到8.0厘米直径的动脉瘤在6个月内破裂率为25.7%.
- 总体死亡率为57%,其中46%进行了尸检.
结论:
- 高手术风险患者的AAA≥5.5厘米具有明显的破裂风险.
- 随着动脉瘤直径的增加,AAA破裂的发生率显著上升.
- 这些发现强调了需要仔细考虑对高风险患者进行干预的必要性,这些患者有大量的AAA.
更多相关视频
相关概念视频
Aortic Regurgitation I: Introduction
1.6K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Aortic Regurgitation III: Medical Management
598
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
598
Aneurysm I: Introduction
658
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
658
Aneurysm II: Clinical Manifestations and Diagnostic Studies
592
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
592
Aneurysm III: Interprofessional Care
478
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
478
Aneurysm IV: Nursing Management
625
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
625

