血管切除术和前列腺癌的风险
Brian Cox1, Mary J Sneyd, Charlotte Paul
1Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago Medical School, PO Box 913, Dunedin, New Zealand. brian.cox@stonebow.otago.ac.nz
JAMA
|June 19, 2002
概括
vasectomy,一个常见的男性避孕方法,不会增加前列腺癌的风险. 这项研究发现,精管切除术与前列腺癌之间没有联系,即使在手术后25多年.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 血管切除术是一种广泛使用的男性避孕方法.
- 人们对 vasectomy 与前列腺癌风险增加之间的潜在联系表示担忧.
研究的目的:
- 为了调查输精管切除术与患前列腺癌的风险之间的关联.
- 为了确定输精管切除是否影响前列腺癌发病率.
主要方法:
- 在新西兰进行了一项基于全国人口的病例控制研究.
- 从923例前列腺癌病例和1224名年龄在40-74岁之间的对照组通过电话采访收集了数据.
- 对那些接受了输精管切除术的男性,与没有接受过的男性进行了前列腺癌的相对风险 (RR) 计算.
主要成果:
- 在输精管切除和前列腺癌风险之间没有发现统计学意义上的关联 (RR,0.92;95% CI,0.75-1.14).
- vasectomy 术后的时间没有改变风险 (RR,0.92; 95% CI,0.68-1.23 ≥25年).
- 调整社会经济因素,地理区域,宗教信仰和家族史并没有改变观察到的结果.
结论:
- 血管切除并没有与前列腺癌的风险增加有关.
- 这一发现甚至适用于切除术后25年以上的男性.
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