霍乱毒素和大肠杆菌耐热性肠内毒素的高亲和性五价值受体结合抑制剂的表征和晶体结构

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Updated: Jul 18, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
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A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

Ethan A Merritt1, Zhongsheng Zhang, Jason C Pickens

  • 1Department of Biochemistry and Biological Structure, University of Washington, Box 357742, Seattle, Washington 98195, USA.

Journal of the American Chemical Society
|July 26, 2002
PubMed
概括

研究人员开发了一种新的五价抑制剂,用于像霍乱毒素这样的细菌毒素. 这种使用m-nitrophenyl-alpha-D-galactoside (MNPG) 的增强抑制剂显著改善了毒素结合亲和力和有效性.

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