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From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
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鉴定Bphs,一个自身免疫性疾病的位置,作为组胺素受体H1的鉴定

Runlin Z Ma1, Jianfeng Gao, Nathan D Meeker

  • 1Laboratory Animal Center, Institute of Genetics, Chinese Academy of Sciences, Beijing, China 100101.

Science (New York, N.Y.)
|July 27, 2002
PubMed
概括

组胺H1受体 (H1R) 基因控制自身免疫反应和血管对Bordetella pertussis毒素的敏感性. 在H1R的遗传变异影响易受自身免疫性疾病和毒素诱导的血管效应.

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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.