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Updated: Jul 10, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

p53:好警察/坏警察

Norman E Sharpless1, Ronald A DePinho

  • 1Department of Adult Oncology, Dana-Farber Cancer Institute, Department of Medicine and Genetics, Harvard Medical School, Boston, MA 02115, USA.

Cell
|August 2, 2002
PubMed
概括

通过阻止受损细胞生长,预防癌症至关重要的p53蛋白质也通过DNA损伤,端粒缩短和氧化应激导致衰老. 针对癌症和衰老的疗法必须绕过,而不是在p53.

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